Blog | Resolve

Best B2B Payment Processing Platforms for Biotech Suppliers

Written by Resolve Team | Feb 12, 2026 3:31:38 PM

Biotech suppliers face a unique financial challenge: managing million-dollar research equipment purchases, navigating complex compliance requirements for clinical trial payments, and coordinating transactions across international research collaborations—all while maintaining cash flow for critical R&D operations. The global biotechnology industry, growing at approximately 12.67% annually and valued at over $2.42 trillion, demands payment platforms that understand high-value transactions, regulatory complexity, and cross-border operations. For biotech suppliers looking to streamline their financial operations while enhancing buyer purchasing power, solutions like Resolve's B2B Net Terms provide the embedded credit expertise needed to offer flexible payment options without sacrificing cash flow.

Key Takeaways

  • Biotech suppliers require specialized payment platforms that handle high-value transactions, complex compliance requirements, and international operations across research collaborations.
  • Offering net payment terms enables biotech suppliers to increase customer purchasing power while platforms like ResolvePay provide non-recourse financing to protect cash flow.
  • Modern AR automation platforms can reduce Days Sales Outstanding (DSO) and administrative overhead while improving credit decision accuracy through AI-powered assessment.
  • Multi-currency support and global payment infrastructure are essential for biotech companies conducting international research partnerships and cross-border equipment sales.
  • HIPAA compliance and PCI-DSS Level 1 certification are critical requirements for platforms handling sensitive clinical data and patient-related payment information.
  • Integration capabilities with existing ERP, accounting, and commerce systems ensure seamless financial operations without disrupting established workflows.
  • Embedded credit solutions allow biotech suppliers to offer flexible payment terms without taking on credit risk, with platforms handling assessment, underwriting, and collections.

1. ResolvePay - Embedded Credit and AR Automation for B2B Growth

ResolvePay offers biotech suppliers a comprehensive solution that combines embedded credit expertise, accounts receivable automation, and non-recourse invoice advancement into a unified platform specifically designed for B2B transactions.

Biotech Supplier Benefits

ResolvePay enables biotech suppliers to offer net payment terms to their customers—research institutions, hospitals, and pharmaceutical companies—without taking on the credit risk or cash flow disruption. This is particularly valuable in biotech where customers often require extended payment terms but suppliers need immediate cash flow for R&D and operations. The platform acts as your complete credit team, handling everything from initial credit assessment through final collections while you focus on core business activities.

The non-recourse financing model means ResolvePay assumes the majority risk of late payments or defaults, protecting your business from bad debt while enabling you to offer competitive payment terms that drive sales growth. This approach transforms extended payment terms from a cash flow liability into a strategic competitive advantage.

Key Features

  • AI-powered credit decisions that evaluate thousands of data points to approve buyer credit lines, enabling instant approvals for purchases up to $25,000 without manual underwriting delays
  • Non-recourse financing that advances up to 90% of invoice value within 24 hours, with Resolve taking on the majority risk of late payments or defaults while protecting your working capital
  • Accounts Receivable automation that streamlines credit assessment, invoicing, payment collection, and reconciliation while reducing Days Sales Outstanding (DSO) through intelligent dunning workflows
  • Seamless integrations with leading ERP, accounting, and commerce platforms including QuickBooks, Oracle, Shopify, and Magento, ensuring synchronized financial data across your tech stack
  • White-label payment portal that accepts ACH, wire, credit card, and check payments while maintaining your brand relationship with customers throughout the payment experience
  • Business credit check services that handle compliance requirements discreetly while providing comprehensive risk assessment for buyer creditworthiness
  • Complete credit team functionality including underwriting, collections management, dispute resolution, and customer communication, eliminating the need to build internal credit departments

Unique Value Proposition

ResolvePay distinguishes itself by offering true embedded credit—not just payment processing. The platform becomes your outsourced credit department, bringing enterprise-level credit expertise to businesses of any size. This is especially valuable for biotech suppliers who need to compete with larger companies that can afford to offer extended terms but lack the resources to manage credit risk internally.

The platform's Net Terms Management solution enables suppliers to increase average order values and win larger contracts by offering payment flexibility that research institutions and healthcare organizations require. By receiving immediate payment while buyers get extended terms, suppliers eliminate the traditional trade-off between cash flow and competitive payment options.

Ideal For

Biotech suppliers are looking to increase sales by offering flexible payment terms while protecting cash flow, reducing administrative overhead, and eliminating credit risk through non-recourse financing.

2. Vellis Financial

Vellis Financial is a payment platform explicitly designed for the biotechnology sector, offering industry-specific compliance and multi-currency capabilities essential for global research operations. Vellis addresses the unique regulatory landscape biotech suppliers navigate, providing PCI-DSS Level 1 certification and HIPAA compliance out-of-the-box. This is critical for suppliers handling sensitive clinical data or processing payments related to patient care. The platform specializes across key biotech verticals including pharmaceutical research, genomics, biomanufacturing, and medical devices.

Key Features

  • Multi-currency accounts supporting 30+ currencies for international research collaborations
  • Custom invoicing tools with built-in payment links specifically designed for lab services and clinical trials
  • Global payment infrastructure with FINTRAC authorization for Canadian operations and worldwide reach
  • Industry-specific compliance handling the complex regulatory requirements unique to biotech transactions

Biotech suppliers require specialized compliance infrastructure and multi-currency support for cross-border research partnerships and high-value equipment sales.

3. QuadraPay

QuadraPay has established itself as a specialist in biotech payment processing since 2016. QuadraPay reports being cited across multiple major international payment industry research reports. QuadraPay understands that biotech transactions often involve complex compliance across multiple jurisdictions and high-value payments for research funding, international supplier arrangements, and specialized equipment. The platform specializes in biotech subsectors including nutraceuticals, diagnostics, peptides, and supplements.

Key Features

  • Fast PSP setup with streamlined online application process
  • Multi-currency transaction support for global research collaborations spanning multiple countries
  • Chargeback mitigation services specifically designed for biotech verticals
  • Automated payment solutions managing invoicing, settlements, and reporting to reduce errors and accelerate workflow

Biotech suppliers in specialized subsectors requiring dedicated payment processing capabilities.

4. Tipalti

Tipalti excels at managing complex global payment operations, making it ideal for biotech companies with extensive international vendor networks including CROs, research labs, and clinical trial sites across multiple countries. Tipalti's strength lies in its comprehensive compliance automation, handling W-8/W-9 collection, 1099 reporting, and international tax requirements that are critical for biotech companies operating across borders.

Key Features

  • Global payment capabilities supporting 200+ countries, 120 currencies, and 50+ payment methods
  • Built-in tax compliance automating W-8/W-9 collection and 1099 reporting across jurisdictions
  • Self-service supplier portal reducing administrative burden for vendor onboarding and management
  • Licensed MSB status enabling faster account approval and regulatory compliance

Companies have achieved significant efficiency gains using Tipalti's platform, with documented 80% reduction in AP processing time. Mid-to-large biotech companies managing complex international vendor payments and requiring robust compliance automation.

5. Billtrust

Billtrust brings specialized expertise from the healthcare and medical supply sector, directly applicable to biotech suppliers. The platform understands the unique challenges of high-value transactions common in healthcare-related industries. Billtrust recognizes that medical and biotech payments can average significantly higher than typical B2B transactions—often exceeding $100,000—requiring specialized handling and compliance. The platform automates complex payment scenarios while maintaining HIPAA compliance.

Key Features

  • Digital Lockbox that automates virtual card processing from AP provider emails while eliminating HIPAA data exposure risks
  • Level 2/3 data processing that can reduce card processing costs by up to 30%
  • AI-powered cash application that handles complex parent/child entity payments typical in hospital and research institution procurement
  • Healthcare-specific compliance with automated HIPAA-compliant virtual card processing

Biotech suppliers selling to healthcare institutions, hospitals, and research organizations requiring specialized AR automation.

6. HighRadius

HighRadius offers comprehensive AR automation for large biotech and pharmaceutical enterprises, processing substantial transaction volumes with Fortune 500 clients including Sanofi. HighRadius leverages AI and machine learning to automate complex AR processes, achieving high straight-through processing rates for cash application. This is particularly valuable for large biotech companies managing receivables from multiple healthcare providers, distributors, and international customers.

Key Features

  • AI-driven credit risk assessment integrating data from 35+ global credit bureaus
  • High straight-through processing rates for cash application, significantly reducing manual intervention
  • Autonomous dunning with ML-optimized send times for payment reminders
  • Fortune 500 client base including major pharmaceutical companies like Sanofi

HighRadius processes over $1T in transactions annually with high cash application accuracy rates. Large biotech and pharmaceutical enterprises require enterprise-grade AR automation with proven scalability.

7. Airwallex

Airwallex specializes in cross-border payments with competitive foreign exchange rates, making it ideal for biotech companies with international research operations, global supplier networks, or customers across multiple countries. Airwallex holds regulatory licenses across Australia, Singapore, Hong Kong, Japan, UK, US, Canada, and EU, ensuring compliant international operations. The platform offers competitive interbank FX rates, crucial for biotech companies making frequent high-value international payments.

Key Features

  • Global multi-currency wallets with dynamic FX rate optimization
  • Competitive interbank FX rates, providing cost-effective international transfers
  • Fast transfer speeds with the majority of transfers arriving within 1 business day, ensuring timely payments to international partners
  • Regulatory licenses across major financial jurisdictions worldwide
  • Powers a substantial number of businesses with significant processing volume

Biotech companies with frequent cross-border payments requiring cost-effective international transfers and multi-currency accounts.

8. Stripe

Stripe provides flexible payment infrastructure for biotech companies that need to build custom payment workflows integrated with lab management systems, research databases, or proprietary platforms. Stripe's advanced APIs and extensive documentation make it suitable for developers building sophisticated biotech payment solutions. The platform scales from startup biotech companies to enterprise pharmaceutical operations.

Key Features

  • Advanced APIs for customizable payment solutions tailored to specific biotech workflows
  • Global payment support with 135+ currencies in 40+ countries
  • Built-in invoicing and subscription management for recurring biotech service billing
  • Extensive developer documentation and community support
  • Standard pricing at 2.9% + $0.30 USD per transaction

Biotech companies with development resources needing to build custom payment integrations or requiring flexibility in their payment infrastructure.

9. Rillion

Rillion offers comprehensive AP automation with healthcare vertical experience, directly applicable to biotech suppliers. The platform serves thousands of companies across healthcare, manufacturing, and hospitality sectors. Rillion's experience with healthcare payment complexity translates well to biotech supplier needs. The platform handles multi-entity management critical for biotech companies with research labs, manufacturing facilities, and offices across multiple locations.

Key Features

  • AI-powered invoice capture with high accuracy across various invoice formats
  • Multi-entity management for companies with multiple locations or subsidiaries
  • Riley AI Assistant providing instant answers about payments, suppliers, and invoices
  • Payment as a Service managing supplier onboarding, preferences, and exception handling
  • 50+ ERP integrations including NetSuite, SAP, Oracle, and Sage

Rillion serves thousands of companies with strong invoice capture accuracy. Mid-market biotech companies require robust AP automation with healthcare industry experience and multi-entity capabilities.

10. Flywire

Flywire brings expertise from the healthcare and education sectors, making it well-suited for biotech suppliers selling to hospitals, research institutions, universities, and medical facilities. Flywire's strength lies in its ability to embed within existing A/R workflows for healthcare and education clients. This vertical-specific approach ensures integration with the complex payment systems used by research institutions and healthcare providers.

Key Features

  • Vertical-specific software embedded in existing A/R workflows for healthcare clients
  • Global payment collection with localized payment methods for international customers
  • Multi-currency support with competitive FX rates for cross-border transactions
  • Healthcare payment expertise with understanding of complex institutional procurement processes

Biotech suppliers whose primary customers are hospitals, research institutions, universities, and other healthcare or educational organizations.

11. Bill.com

Bill.com offers accessible AP/AR automation for early-stage and small biotech companies needing to automate supplier payments without enterprise-level complexity. Bill.com's simple interface and extensive vendor network make it suitable for smaller biotech companies beginning to scale their operations. The platform's substantial vendor network means many lab suppliers are likely already in the system.

Key Features

  • Extensive vendor network of millions of suppliers for fast, secure payments
  • Automated AP/AR workflows with seamless QuickBooks and Xero integration
  • Multiple payment options including ACH, wire transfer, and check
  • User-friendly interface requiring minimal training or technical expertise

Early-stage and small biotech companies needing affordable, simple payment automation.

12. Wise Business

Wise Business provides cost-effective solutions for small-to-mid biotech companies making frequent international payments to suppliers, CROs, or research partners. Wise Business offers transparent pricing, displaying real mid-market exchange rates upfront. This transparency is valuable for biotech companies operating on research budgets.

Key Features

  • Multi-currency accounts with local account details in 40+ currencies
  • Real mid-market exchange rates with transparent fees
  • Batch payment capabilities for multiple international supplier payments
  • Simple, fast setup suitable for smaller biotech companies
  • Operations in 160+ countries with global payment reach

Small-to-mid biotech companies making frequent international payments who prioritize transparent pricing and cost-effectiveness.

Making Your Choice: Essential Considerations for Biotech Suppliers

Selecting the right payment platform depends on your specific operational needs, growth stage, and strategic objectives. For biotech suppliers looking to increase sales by offering net payment terms while protecting cash flow, ResolvePay's comprehensive Net Terms Management solution provides the embedded credit expertise, non-recourse financing, and AR automation needed to compete effectively without taking on credit risk.

Company Size and Complexity: Large biotech enterprises with complex global operations may benefit from enterprise-grade automation platforms like HighRadius or Tipalti. Mid-market companies often find balanced capabilities in platforms like Rillion or ResolvePay. Small biotech startups may prefer accessible options like Bill.com or Wise Business.

Compliance Requirements: Suppliers handling sensitive health data or clinical trial payments require HIPAA-compliant platforms like Vellis Financial, Billtrust, or ResolvePay's Business Credit Check services that handle compliance requirements appropriately.

Global Operations: Companies with international research collaborations or supplier networks should prioritize platforms with strong multi-currency support like Airwallex, Vellis Financial, or Wise Business.

Credit Terms Strategy: Biotech suppliers looking to win larger contracts and increase average order values by offering net payment terms should consider ResolvePay's approach, which provides non-recourse financing while handling credit assessment and collections, eliminating the traditional trade-off between competitive payment terms and cash flow protection.

Integration Needs: Ensure your chosen platform integrates with your existing ERP, accounting, and commerce systems. ResolvePay offers extensive integrations with platforms like QuickBooks, Oracle, Shopify, and Magento for seamless financial operations.

Why ResolvePay Stands Out for Biotech Suppliers

Biotech suppliers can turn payment terms into a growth driver with ResolvePay’s embedded credit model. You can offer the flexible terms research institutions and healthcare buyers expect while getting paid immediately and removing credit risk through non-recourse financing. AI-powered credit decisions analyze thousands of data points to deliver instant approvals for purchases up to $25,000, keeping sales moving while maintaining rigorous risk standards.

ResolvePay advances up to 100% of approved invoice value within 24 hours, supporting working capital for critical R&D operations and equipment needs. It also functions as your outsourced credit team—managing credit assessment through collections—so you don’t need to build an internal department to compete with larger suppliers. The accounts receivable automation streamlines invoicing, collection, and reconciliation to reduce DSO. A white-label portal preserves your brand and accepts ACH, wire, card, and check, with ERP/accounting integrations to keep data synced.

Frequently Asked Questions

What are the primary benefits of using a specialized B2B payment platform for a biotech supplier?

Specialized B2B platforms fit biotech needs: high-value orders (often $100K+), HIPAA/PCI-DSS compliance, and international payments. They add automated compliance handling, multi-currency support, and biotech workflows, plus net terms with immediate payment via non-recourse financing.

How do net payment terms help biotech suppliers grow their revenue and customer base?

Net terms boost buyer purchasing power so institutions can place larger orders without upfront cash. That flexibility helps you win deals from bigger competitors. ResolvePay lets you offer net terms while receiving immediate payment through non-recourse financing.

What is the difference between a payment processor and a comprehensive B2B payment platform, and which is better for biotech?

Payment processors only authorize and settle transactions. Comprehensive B2B platforms manage credit assessment, AR automation, compliance, and global payments end to end. For biotech, full platforms are usually better because they support complex, high-value, regulated sales.

Can B2B payment platforms integrate with my existing ERP or accounting software like QuickBooks?

Yes. Many platforms integrate with ERPs and accounting tools to sync invoices, payments, and reconciliation automatically. ResolvePay connects with accounting, and commerce platforms like QuickBooks, Oracle, Shopify, and Magento to reduce manual entry and errors.

What does non-recourse invoice advancement mean, and how does it benefit my biotech business?

Non-recourse advancement means the platform takes customer non-payment risk—if the buyer doesn’t pay, you keep the funds. ResolvePay offers non-recourse financing, advancing up to 90% within 24 hours, protecting cash flow and reducing bad debt.

This post is to be used for informational purposes only and does not constitute formal legal, business, or tax advice. Each person should consult his or her own attorney, business advisor, or tax advisor with respect to matters referenced in this post. Resolve assumes no liability for actions taken in reliance upon the information contained herein.